The cheapest times to fly from TYS to MYR are

  • January 1st to February 25th
  • July 2nd to July 15th
  • August 13th to December 16th (except the weeks of October 1st, November 19th, and November 26th)

based on data collected exclusively by Champion Traveler across tens of millions of flights. Among all the dates above, the very cheapest time to fly from TYS to MYR is early to mid September. Prices can be as high as $562 for Sunday flights during early to mid March, or as low as $155 for Wednesday flights around early to mid September.


When to Fly to Myrtle Beach

Flying from Knoxville, TN (TYS) to Myrtle Beach, SC (MYR) will usually cost between $175 to $380 per person if booking more than four weeks in advance. On average the very cheapest time to fly is early to mid September with an average ticket price of $178. Due to high demand the most expensive time to fly is early to mid March, with an average price of $380. Planning your trip to low-cost times can easily save you $202 on economy flights and even more on first-class flights. Generally, any price below $262 can be considered a good price for a round-trip TYS to MYR flight.

See below for a graph of average weekly prices for the TYS to MYR route. All prices are for round-trip tickets in USD.

TYS to MYR Flight Prices

Compared to other flights, the TYS to MYR flight is much cheaper than the average and costs much less than the average flight leaving from Knoxville. The average price per mile (for a direct flight) is $0.5, which is above average.


Flight Prices by Day of the Week

Wednesday is usually the cheapest day to fly to MYR, and Tuesday the cheapest day to fly back into TYS. Sundays are the most expensive days to fly out or take a return trip. Selecting flights on the least expensive days could save you up to $108 (32%) on this flight.

Departing prices are for round-trip flights returning on the day of departure. For example, a flight departing on Wednesday and returning a week later will cost an average of $224. Return trip prices are from the MYR to TYS flight, and often highlight the quality of our data in showing the same trend.

Departing Prices by Day

Departure Day Prices

Return Trip Prices by Day

Return Day Prices


Nonstop Flights and Layovers

Travelers looking to fly from TYS to MYR can generally find a 1-layover flight. Because there is not usually a direct flight option the real-world direct flight time of 1 hour 34 minutes may not be realistic.


Alternative Nearby Airports

Champion Traveler tells you which airports are nearby and whether tickets might be cheaper alternative airports nearby. Sometimes it’s worth it to fly into a closer airport and then commute to your destination. Remember that there is not usually a nonstop flight from TYS to MYR while comparing.

Destination alternative #1: Charleston AFB/International Airport (CHS) in Charleston, SC

  • 84 miles (135 km) away from MYR
  • Usually 2.49% less expensive than MYR
  • 1-layover flights available

See TYS to CHS flights

Destination alternative #2: Wilmington International Airport (ILM) in Wilmington, NC

  • 72 miles (116 km) away from MYR
  • Usually 1.91% less expensive than MYR
  • 1-layover flights available

See TYS to ILM flights

Destination alternative #3: Hilton Head Airport (HHH) in Hilton Head, SC

  • 144 miles (232 km) away from MYR
  • Usually 1.91% less expensive than MYR
  • 1-layover flights available

See TYS to HHH flights

Destination alternative #4: Coastal Carolina Regional Airport (EWN) in New Bern/Morehead/Beaufort, NC

  • 144 miles (232 km) away from MYR
  • Usually 1.91% less expensive than MYR
  • 1-layover flights available

See TYS to EWN flights


Flight Questions Answered

Still have questions about flying from TYS to MYR? We’ve got answers.

Which airlines fly this route?

You can find 4 major airlines flying this route most often: American, Delta, Frontier, United, and potentially more during busy seasons.

How far away is it from Myrtle Beach International Airport to McGhee Tyson Airport?

The distance between the two airports is roughly 323 miles or 520 kilometers.

How long does it take to fly from TYS to MYR?

The real-world flight time for a nonstop TYS to MYR flight is about 1 hour 34 minutes.

How many flights go between Knoxville, TN and Myrtle Beach, SC?

It depends on the day of the week and the date, but a typical day might have around 48 available flights from TYS to MYR.


Airport Location Info


Departing Airport

Origination codeTYS
Origination airport nameMcGhee Tyson Airport
CityKnoxville, TN
Countrythe United States

Return Airport

Destination codeMYR
Destination airport nameMyrtle Beach International Airport
CityMyrtle Beach, SC
Countrythe United States


Other Resources

Please note that while we’ve worked hard to analyzed tens of millions of flights to get you this data, we do not calculate current live prices or guarantee pricing. Please see our partners using the links above for current offers.