The cheapest times to fly from LSE to TYS are

  • January 8th to February 25th
  • May 7th to August 5th (except the weeks of May 21st, June 18th, and June 25th)
  • October 29th to November 18th

based on data collected exclusively by Champion Traveler across tens of millions of flights. Among all the dates above, the very cheapest time to fly from LSE to TYS is early December. Prices can be as high as $612 for Sunday flights during mid to late November, or as low as $184 for Tuesday flights around early December.


When to Fly to Knoxville

Flying from La Crosse, WI (LSE) to Knoxville, TN (TYS) will usually cost between $185 to $468 per person if booking more than four weeks in advance. On average the very cheapest time to fly is early December with an average ticket price of $218. Due to high demand the most expensive time to fly is mid to late November, with an average price of $402. Planning your trip to low-cost times can easily save you $184 on economy flights and even more on first-class flights. Generally, any price below $252 can be considered a good price for a round-trip LSE to TYS flight.

See below for a graph of average weekly prices for the LSE to TYS route. All prices are for round-trip tickets in USD.

LSE to TYS Flight Prices

Compared to other flights, the LSE to TYS flight is much cheaper than the average and costs much less than the average flight leaving from La Crosse. The average price per mile (for a direct flight) is $0.23, which is below average.


Flight Prices by Day of the Week

Tuesday is usually the cheapest day to depart and return on this flight. Sundays are the most expensive days to fly out or take a return trip. Selecting flights on the least expensive days could save you up to $143 (37%) on this flight.

Departing prices are for round-trip flights returning on the day of departure. For example, a flight departing on Tuesday and returning a week later will cost an average of $200. Return trip prices are from the TYS to LSE flight, and often highlight the quality of our data in showing the same trend.

Departing Prices by Day

Departure Day Prices

Return Trip Prices by Day

Return Day Prices


Nonstop Flights and Layovers

Travelers looking to fly from LSE to TYS can generally find a 1-layover flight. Because there is not usually a direct flight option the real-world direct flight time of 2 hour 12 minutes may not be realistic.


Flight Questions Answered

Still have questions about flying from LSE to TYS? We’ve got answers.

Which airlines fly this route?

You can find 4 major airlines flying this route most often: American, Delta, Iberia, United, and potentially more during busy seasons.

How far away is it from McGhee Tyson Airport to La Crosse Regional Airport?

The distance between the two airports is roughly 677 miles or 1090 kilometers.

How long does it take to fly from LSE to TYS?

The real-world flight time for a nonstop LSE to TYS flight is about 2 hour 12 minutes.

How many flights go between La Crosse, WI and Knoxville, TN?

It depends on the day of the week and the date, but a typical day might have around 17 available flights from LSE to TYS.


Airport Location Info


Departing Airport

Origination code LSE
Origination airport name La Crosse Regional Airport
City La Crosse, WI
Country the United States
Latitude 43.9
Longitude -91.3

Return Airport

Destination code TYS
Destination airport name McGhee Tyson Airport
City Knoxville, TN
Country the United States
Latitude 35.8
Longitude -84


Other Resources

Please note that while we’ve worked hard to analyzed tens of millions of flights to get you this data, we do not calculate current live prices or guarantee pricing. Please see our partners using the links above for current offers.